The diagnosis ofpitted keratolysis is clinical 5). Vlahovic, TC, Dunn, SP, Kemp, K. The use of clindamycin 1%-benzoyl peroxide 5% topical gel in the treatment of pitted keratolysis: a novel therapy. This condition can cause itchiness and smelly feet. J Eur Acad Dermatol Venereol 2013;27:11206. U.S. STD Cases Increased During COVIDs 2nd Year, Have IBD and Insomnia? Pranteda G, Carlesimo M, Pranteda G, et al. Pitted keratolysis, when not treated, might get worse as these pits might coalesce and form larger pits and the smell from your feet might get even worse. readers, especially in skin of colour: Copyright 1994 - 2021 The Primary Care Dermatology Society. Also, length of sessions about Pitted keratolysis merupakan suatu infeksi bakteri pada kulit yang menyebabkan terbentuknya lubang-lubang kecil di lapisan atas kulit. Pregnancy-related Pitted keratolysis, erythromycin, and hyperhidrosis. Infection. These tend to be round and are typically 0.5 millimeters to 7 millimeters in diameter. Mouth Treatment Options Treatment options are summarized in Table I. If you would like to donate, please use this Arms and legs Pitted keratolysis is reported to be more common among barefooted laborers/farmers, marine workers, soldiers and industrial workers wearing occluded shoes for prolonged periods. Most commonly occurring in athletes and members of the military, pitted keratolysis is a non-contagious skin infection that affects the soles and other weight bearing areas of the foot. Hyperhidrosis is a condition that causes excessive sweat across the body, including the feet. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401600/. Sex: males > females. Pitted keratolysis is a descriptive term for a superficial bacterial skin infection that affects the soles of the feet, and less often, the palms of the hands 1). They proliferate and produce protease enzymes that cause destruction of the stratum corneum to create pits/craters. Vlahovic TC, Dunn SP, Kemp K. The use of a clindamycin 1%benzoyl peroxide 5% topical gel in the treatment of pitted keratolysis: a novel therapy. Pitted keratolysis is a superficial, and sometimes malodorous, infection of the pressure-bearing aspects of the feet, characterised clinically by crateriform pitting. The odor is felt to be caused by the digestive action of the enzymes on the keratin producing a myriad of thiols and thioesters. The malodor associated with pitted keratolysis is presumed to be due to the production of sulfur-compound by-products, such as thiols, sulfides and thioesters 17). It's an overgrowth of various bacteria normally present in the skin due to excessive moisture and lack of aeration. Distribution: plantar feet, web spaces of feet Predisposition: hyperhidrosis and Occlusive footwear Clinical findings: defects in thickly keratinized skin with eroded pits of variable depth Usually asymptomatic. vol. - And More, (Four males with pitted keratolysis were treated with a combination of clindamycin and benzoyl peroxide gel once a day. Pitted keratolysis is caused by an infection of the stratum corneum by Kytococcus sedentarius (formerly Micrococcus spp. Angelica Bottaro is a professional freelance writer with over 5 years of experience. given and further information. Regularly rotating or airing out shoes is also a good way to deal with this condition. The most common symptom of the condition is a foul smell coming from the feet. However, it frequently impacts the feet because of the sweaty environment developed by wearing shoes and socks for an extended period of time.This condition is identified by little depressions or pits in the top layer of skin and locations of white skin. Int J Dermatol. The most indicated materials for socks are wool and cotton. Woodgyer AJ, Baxter M, Rush-Munro FM. These bacteria thrive in a wet environment and produce enzymes as well as sulfur compounds. There is a variant of pitted keratolysis where there are more diffuse red areas on the soles. The treatments consist either of topical or oral antibiotics. ), Vazquez-Lopez, F, Perez-Oliva, N. Mupirocin ointment for symptomatic pitted keratolysis. If you notice any odd symptoms, such as pits in the feet or a strong and foul foot odor, visit your healthcare provider. GP Leeds, "I think it was one of the best courses for GPs I have attended If you have an underlying skin condition such as excessive sweating also known as Hyperhidrosis, your dermatologist might add other drugs to deal with that too. Pitted keratolysis can occur in people of any race, any age, and either sex, though it is more common in males. The condition is characterised by conspicuous, discrete, shallow, and circular pits, with a punched out appearance. Many experiments were performed to determine the optimal pH, temperature and other factors on enzyme activity level. Adv Skin Wound Care. Patients need to be educated on proper foot care. Do not share footwear or towels with others. 2012;4(1):e4. Your use of this website constitutes acceptance of Haymarket Medias Privacy Policy and Terms & Conditions. Dermatol Ther. Nails Pitted keratolysis is a skin condition affecting the soles of the . He cleared totally in 8 weeks. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. Pitted keratolysis and tinea pedis was seen at significantly higher rates in patients with hyperhidrosis. [Journal of Current and Advance Medical Research 2017;4(1):27-30] This review is aimed to consolidate present information about aetiopathogenesis, diagnosis and management of Pitted Keratolysis. In the summer and especially during hot summer days, open toed sandals are the adequate footwear. Yes. Pitted keratolysis is one of the causes of smelly feet. J Am Acad Dermatol. ), (In vitro studies purifying the P1 and P2 proteins. Which is a highly contagious primary infection caused by the herpes varicella-zoster virus, characterized by successive crops of small blisters which can evolve into pustules, crusts and even scars. Can pitted Keratolysis go away by itself? Pitted keratolysis isn't contagious, so you're not going to get it from public showers etc. Pitted keratolysis. The number . In some rarer cases, the condition can also develop on the palms of the hands. Pitted keratolysis is a medical condition in which the skin on the feet and toes becomes infected with bacteria, due to a combination of factors (often times because of the inadequate footwear, poor hygiene and excessive sweating). Benzoyl Peroxide gel might be prescribed as an antiseptic. Either the forefoot or the heel or both become white with clusters of punched-out pits. Chlorhexidine Scrub, ZnO Nanoparticles Socks and the Combination for Treatment of Pitted Keratolysis (PK_treatment) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. It is generally caused by either Staphylococcus aureus or streptococci. is implicated 6). PonyWang / Getty Images This is more common in certain professions eg those working in Paddy fields, Limit the use of occlusive footwear (if possible) and reduce skin friction by wearing properly fitted footwear, Use moisture absorbing innersoles. However, the infection can occur in anyone that wears occlusive footwear and has excessively sweaty feet. ), Gurcharan, S, Chandra, N. Pitted keratolysis. These 13-millimetre pits are more prominent when your feet are wet, and make the skin look white and wrinkly. Pitted keratolysis is a skin disorder characterized by crateriform pitting that primarily affects the pressure-bearing aspects of the plantar surface of the feet and, occasionally, the palms of. Urticaria and angioedema 30. Can you get pitted keratolysis somewhere other than the feet? Int J Dermatol 2008;47:88490. 1,2 The microorganism apparently invades the upper two thirds of the keratin layer by means of its hydrolytic enzymatic activity. The strong odor is due to sulfur compounds made by bacteria as they break down the skin. Fungal infections (tinea) 15. Our articles were written by fully qualified doctors of medicine and general practioners. Thank you, Thank you very much, you have been so helpful. If scaling is present a potassium hydroxide ((KOH) examination should be done to determine if there is a co-existing dermatophyte infection. Pitted keratolysis is easily identified by its shallow, crater-like pits. 2005 May-Jun; 71(3):213-5. van der Snoek EM, Ekkelenkamp MB, Suykerbuyk JC. Pitted keratolysis is caused by different species of bacteria. The differential diagnosis is narrow. Pitted keratolysis (also known as Keratolysis plantare sulcatum, [1] Keratoma plantare sulcatum, [1] and Ringed keratolysis [1]) is a bacterial skin infection of the foot. If necessary, they may also prescribe drying agents such as Drysol. Copyright 2017, 2013 Decision Support in Medicine, LLC. It is highly treatable with antibiotics. vol. Preventive measures might help you avoid pitted keratolysis in the future, and these include, wearing sweat absorbable socks and avoiding wearing footwear for longer periods. Corynebacterium-associated skin infections. It is not felt to be an infection that is contagious. Optimal Therapeutic Approach for this Disease, Unusual Clinical Scenarios to Consider in Patient Management, Use of cedar shoe trees can decrease moisture in shoes, Wear a different pair of shoes every other day, Wash feet daily and completely dry skin after bathing, Wash socks on high temperature to kill the bacteria. K sedentarius has been found to produce two keratin digesting proteins. Indian J Dermatol Venereol Leprol. Pain / tenderness (sore to touch) and health professionals, Up to 30% of GP consultations have some element of skin, but yet there is limited A few cases of concurrent dermatophyte infection with pitted keratolysis have been described. Craterlike pits on the feet and toes (the toes are affected in rare cases). Takama H, Tamada Y, Yano K, Nitta Y, Ikeya T. Pitted keratolysis. If the feet have been recently washed fluorescence is unlikely to be seen. The feet also commonly have an associated bad odor. eMedicine J 2003;11:1-7. A lot of patients diagnosed with pitted keratolysis have social anxiety because of their smelly feet. google_ad_client: "ca-pub-9759235379140764", Clinical features: characteristic pits and maceration smell of rotten fish this condition is more common in young men who wear training shoes Management: breathable footwear topical fusidic acid Pityriasis versicolor 24. The feet need to be cleaned with antibacterial soap or a cleaner with antiseptic properties. These are the most common symptoms of pitted keratolysis: Pitted keratolysis is caused by the infection with different types of bacteria, including any of the following: What happens is that bacteria appears on a thriving environment, where is a lot of restriction, humidity because of the excessive sweating and a modification of the skin pH. conditions, Other useful tools for patients and 55(Case series of four patients treated with mupirocin ointment. Pictures and symptoms of the red, scaly rash. Pitted keratolysis can be successfully treated with topical antibiotics and antiseptics including: Oral erythromycin is also helpful, may shorten the treatment period 23). The superficial erosion is found under the toes and the soles of the feet, these being the areas where the weight bearing is accentuated. Hyperhidrosis is found in approximately 70% of cases. Do not share footwear or socks with other people, as you might borrow their infections and suffer from other complications. Fordyce's granules), Adult (Four males with pitted keratolysis were treated with a combination of clindamycin and benzoyl peroxide gel once a day. Others with a worse infection may need antibiotics for as long as eight weeks. The treatment for pitted keratolysis depends entirely on the severity of the infection. use, THE CUNLIFFE (TP) SKIN LESION DIAGNOSTIC TABLE, Trunk (chest, abdomen, back) / buttocks / axillae / groin, Leg & Other This can be accomplished with a hair dryer on low heat. Pitted keratolysis - a study of various clinical manifestations. (Do not recommend this in patients with diabetes or neuropathy they may burn the skin). These two proteins named P1 and P2 are serine protease enzymes that can easily digest human keratin. ((Pitted keratolysis. Three to four percent of patients with pitted keratolysis may also have erythrasma and/or trichomycosis. Pitted keratolysis, erythromycin, and hyperhidrosis. The most commonly reported symptom is malodor. J Invest Dermatol 1986;87:159. ), though Dermatophilus congolensis and Corynebacterium spp. Pitted keratolysis is a skin condition affecting the soles of the feet and, less commonly, the palms of the hands. Can you send a link please for babys feet? Our simple consultation first process enables you to complete a consultation with a doctor, submitting photos of the affected skin and answering a set of questions that will enable a diagnosis where possible. Pits or holes in the skin that typically develop over, Pits can be brown and more visible when the feet are wet, A feeling of wetness or sliminess on the feet, Thickening of the outer layer of skin on the soles of the feet, Lightening of the skin on the soles of the feet, An inflamed, red rash on the bottom of the feet, Around the nails on both the hands and the feet, Athletes or others involved in sports activities. A variant of pitted keratolysis presents with diffuse red areas on the soles. 1109376 Lead Author - Dr Tim Cunliffe. It is an acquired, chronic, superficial bacterial infection . The lesions tend to be multiple, superficial rounded depressions, 0.5 to 7 mm in diameter, affecting mainly weight-bearing areas of the soles. Healthcare providers diagnose pitted keratolysis based on its clinical appearance and odor. Moisture and inappropriate hygiene may be the predisposing factors in such patients. Background: Pitted keratolysis is a bacterial infection that affects the plantar epidermis. Lockwood LL, Gehrke S, Navarini AA. It is also important to note that pitting keratolysis is non-contagious. A new form of treatment. Pitted keratolysis may be a sign of other Corynebacterium infections and one should consider looking for evidence of erythrasma and/or trichomycosis. If the patients have cleared, therapy can be discontinued after 4 weeks. Antiperspirant can be applied to the feet in order to reduce and prevent the excessive sweating. This can help them find out what kind of bacteria is causing your pitted keratolysis.. What are the Causes of Pitted Keratolysis? 39. A 30-year-old male presented with small punched-out. In some patients, the condition is caused by an overgrowth of normal flora. 2005. pp. No, pitted keratolysis isn't contagious and can't spread from person to person. (Nice review of Cornebacterium skin infections, including pitted keratolysis, erythrasma, and trichomycosis. As for oral antibiotics, erythromycin is the most recommended. Itch Pitted keratolysis is characterized by whitish skin and clusters of punched-out pits. Talk to your doctor instead of relying on over-the-counter products which may make your pitted keratolysis worse. It creates crater-like pits or small holes on the top layer of your skin and usually affects the soles of your feet, but can. Protection Policy. 50U of boltulinum toxin total was injected into each sole (25 different areas were injected). The authors hypothesized that decreasing sweating cured the pitted keratolysis. However, it is advisable to maintain good personal hygiene. As many as 100% of people with the condition will have this particular symptom. The pitting is due to destruction of the horny cells (stratum corneum) by protease enzymes produced by the bacteria. Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor. Occasionally, pitted keratolysis can be confused with tinea pedis, but pitted keratolysis is associated with a strong foul odor and usually manifests as small crateriform depressions of the soles and heels. Patients may experience hyperhidrosis (excessive sweating), foot odor and sometimes itching or burning while walking, although most cases are asymptomatic 3). Latest News Your top articles for Tuesday, Continuing Medical Education (CME/CE) Courses. ), Schissel, DJ, Aydelotte, J, Keller, R. Road rash with a rotton odor. The British Association of Dermatologists has released its latest position state General Dermatology Diagnostic Tool 2008 Sep; 47(9):884-90. It has both aerobic and anaerobic antibacterial properties due to . 213-5. The physician should assess for hyperhidrosis. Proceeding of the XIII International Congress of Dermatology 1967;593-5. In severe refractory cases oral erythromycin 500mg orally twice daily for 14 days can be considered. Military Medicine. English JC. Scalp Prognosis is excellent, and lesions usually resolve in three to four weeks 27). 24. 1. Other common symptoms include: While the soles of the feet are the most commonly affected areas, the condition can develop in other places, such as: In many cases, people with pitted keratolysis do not experience any symptoms. 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Copyright 2017, 2013 Decision Support in medicine, LLC the Primary Care Dermatology Society cells stratum! A cleaner with antiseptic properties including pitted keratolysis is one of the horny cells stratum. International Congress of Dermatology 1967 ; 593-5 was injected into each sole ( 25 different areas were )! Qualified doctors of medicine and general practioners or a cleaner with antiseptic properties is characterized by skin... Care Dermatology Society of this website constitutes acceptance of Haymarket Medias Privacy Policy and Terms & Conditions lapisan atas.... On over-the-counter products which may make your pitted keratolysis is a skin condition the... Conditions, other useful tools for patients and 55 ( Case series four. Bacteria normally present in is pitted keratolysis contagious skin due to sulfur compounds out what kind of bacteria link for. Dermatology Society articles for Tuesday, Continuing Medical Education ( CME/CE ) Courses,... 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Copyright 1994 - 2021 the Primary Care Dermatology Society, you have been recently washed fluorescence is unlikely to round! Terbentuknya lubang-lubang kecil di lapisan atas kulit spread from person to person the! Rare cases ) normal flora easily digest human keratin excessive sweating of its hydrolytic activity! Red areas on the feet have been so helpful is characterised by conspicuous, discrete,,. Environment and produce enzymes as well as sulfur compounds on proper foot Care red areas the. Qualified doctors of medicine and general practioners is more common in males more... Be considered sweat across the body, including the feet, characterised clinically crateriform! It & # x27 ; t contagious and can & # x27 ; t spread from person person... Have been so helpful a condition that causes excessive sweat across the body, including the.. Down the skin due to sulfur compounds made by bacteria as they down... 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